Glossary

Amniotic fluid

the protective fluid surrounding an embryo in mammals. 

Animal pole

the region where cells are mainly localized - the opposite pole is the vegetal pole, where the yolk is mainly localized.

Anterior-posterior axis

one of the body axis running from the head of the organism down to the lower limbs.

Arthropod

an invertebrate without an internal skeleton, instead the organism is protected by an external case - an exoskeleton.

Blastpore

 a hole in the embryo which opens on to the primitive gut.

Blastula

the early embryo simply consisting of a ball of cells.

Cadherin

a cell adhesion molecule.

CAM

 Cell adhesion molecules - molecules which allow cell-cell and cell-extra cellular matrix binding.

Differentiation

  the specialization of a cell’s fate into a certain pathway - e.g. neural, muscle etc.

Dorsal

 the dorsal or back of the organism. The dorsal-ventral axis is one of the body axis, others are the anterior (head) to posterior (feet) axis. 

Glia

non neuronal cells present in the nervous system, which support neurons and play important roles in signaling.

Growth factor

a secreted signaling molecule that can induces growth in receptive cells. 

Homolog

see homologous.

Homologous

two proteins in different species with very similar DNA sequences.

Medio-lateral

one of the body axis running from the midline of the body across to the outer side.

Mesenchyme

a cell type that can migrate through tissues and does not have regular tissue boundaries or cell-cell adhesion.

Midline

an imaginary line running down the middle of an organism.

Morphogen

a secreted signaling molecule which causes different effects on cells in a concentration-dependent way. 

Neuroblast

a partially differentiated cell who will either differentiate into a neuron or glia cell.

Organizer

a group of cells which secrete morphogens and induce cell fate throughout the embryo.

Organogenesis

the process where, after Gastrulation, the three germ layers begin to create the major internal organs.

Pluripotent

a non-differentiated cell which can develop into any cell in the adult body. 

Precursor

a cell, which hasn’t fully transitioned into it’s final state.

Proliferation

cell division and growth - vital in the embryo as a single cell creates an entire organism.

Somite

groups of mesodermal cell distributed along either side of the neural tube. They form vertebrae amongst other things.

Transcription factor

a DNA binding protein which increases transcription of certain genes.

Vegetal pole

 the pole at which mostly yolk is localized. See dorsal pole.

Ventral

 the front side of the embryo - see dorsal.

Yolk

nutrient-rich fluid attached to embryos who are not able to get nutrients from their mother via a sack. Found in amphibians, reptiles and birds.